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Article

Bax-induced cell death in yeast depends on mitochondrial lipid oxidation.

European journal of biochemistry - 1 Nov 2002

Priault Muriel, Bessoule Jean-Jacques, Grelaud-Coq Angela, Camougrand Nadine, Manon Stéphen

Abstract excerpt

The oxidant function of pro-apoptotic protein Bax was investigated through heterologous expression in yeast. Direct measurements of fatty acid content show that Bax-expression induces oxidation of mitochondrial lipids. This effect is prevented by the coexpression of Bcl-xL. The oxidation actually...

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Identifiers

PMID: 12423342
DOI: 10.1046/j.1432-1033.2002.03234.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12423342-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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