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Article

Biochemical and genetic analysis of the mitochondrial response of yeast to BAX and BCL-X(L).

Molecular and cellular biology - 1 May 2000

Gross A, Pilcher K, Blachly-Dyson E, Basso E, Jockel J, Bassik M C, Korsmeyer S J, Forte M

Abstract excerpt

The BCL-2 family includes both proapoptotic (e.g., BAX and BAK) and antiapoptotic (e.g., BCL-2 and BCL-X(L)) molecules. The cell death-regulating activity of BCL-2 members appears to depend on their ability to modulate mitochondrial function, which may include regulation of the mitochondrial perm...

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Source

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Identifiers

PMID: 10757797
DOI: 10.1128/MCB.20.9.3125-3136.2000
PMCID: PMC85607

Genes

BAX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-10757797-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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