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Article

Methods of assaying Bcl-2 and Bax family proteins in yeast.

Methods (San Diego, Calif.) - 1 Apr 1999

Xu Q, Jürgensmeier J M, Reed J C

Abstract excerpt

Bcl-2 family proteins play an evolutionarily conserved role in regulating the life and death of the cell. Certain proapoptotic members of the Bcl-2 family, Bax and Bak, have intrinsic cytotoxic activities in that they not only induce or sensitize mammalian cells to undergo apoptosis but also display a lethal phenotype when ectopically expressed in two yeast species Saccharomyces cerevisiae and Schizosaccharomyces...

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Identifiers

PMID: 10196100
DOI: 10.1006/meth.1999.0743

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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