Article
Mapping the nucleolar proteome reveals a spatiotemporal organization related to intrinsic protein disorder
2020-01-30
Abstract excerpt
The nucleolus is essential for ribosome biogenesis and is involved in many other cellular functions. We performed a systematic spatiotemporal dissection of the human nucleolar proteome using confocal microscopy. In total, 1,318 nucleolar proteins were identified; 287 were localized to fibrillar components, and 157 were enriched along the nucleoplasmic border, indicating a potential fourth nucleolar subcompartment...
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Identifiers and source
- Literature Corpus work
- 72e7cc6f-6468-5c1d-845e-20345306f58d
- DOI
- 10.1101/2020.01.30.923003