Role of Biomarkers for the Diagnosis of Prion Diseases

Abstract excerpt

Prion diseases are progressive and irreversible neurodegenerative disorders with a low incidence (1.5–2 cases per million per year). Genetic (10-15%), acquired (anecdotal) and sporadic (85%) forms of the disease have been described. The clinical spectrum of prion diseases is very varied, although the most common symptoms are rapidly progressive dementia, cerebellar ataxia and myoclonus. Mean life expectancy...

Topics

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• Creutzfeldt-Jakob Syndrome
• Early Diagnosis
• Encephalitis
• Genotype
• Mutation
• Phenotype
• Prion Diseases
• Prion Diseases and Protein Misfolding

Identifiers and source

Literature Corpus work

72e006f6-d517-58b3-9136-d829cc5cec2c

DOI

10.20944/preprints202202.0308.v1