Article
Clinical Use of Improved Diagnostic Testing for Detection of Prion Disease.
Viruses - 28 Apr 2021
Figgie Mark P, Appleby Brian S
Abstract excerpt
Prion diseases are difficult to recognize as many symptoms are shared among other neurologic pathologies and the full spectra of symptoms usually do not appear until late in the disease course. Additionally, many commonly used laboratory markers are non-specific to prion disease. The recent introduction of second-generation real time quaking induced conversion (RT-QuIC) has revolutionized pre-mortem diagnosis of...
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