Article

ENHANCED CLEAVAGE OF GENOMIC <i>CCR5</i> USING CASX2 <sup>Max</sup>

2025-07-11

Abstract excerpt

Development of novel CRISPR/Cas systems enhances opportunities for gene editing to treat infectious diseases, cancer, and genetic disorders. We evaluated CasX2 ( Plm Cas12e), a class II CRISPR system derived from Planctomycetes , a non-pathogenic bacterium present in aquatic and terrestrial soils. CasX2 offers several advantages over Streptococcus pyogenes Cas9 ( Sp Cas9) and Staphylococcus aureus Cas9 ( Sa...

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Literature Corpus work: 72ab350f-f925-5637-bbd6-fb681159d9c9
DOI: 10.1101/2025.07.08.663680

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