Article

HIV-1: Tackling the Obstacles that Limit the Effectiveness of CRISPR-Cas9 Gene Editing of the T Cell Co-receptor CCR5

2020-04-13

Abstract excerpt

HIV-1 is a complicated and perplexing virus. It infects T cells, reverse transcribes its RNA into DNA, utilizes its host DNA machinery to replicate its HIV-DNA, translates the HIV-DNA into proteins, assembles itself for a budding escape from the T cell, and rapidly mutates its conformation. Partially, due to its complexity, there remains no cure for HIV or AIDs. However, recently with the discovery of TALENs, the...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d33e9e75-a17f-55ca-b1db-37176faa106c
DOI: 10.20944/preprints201907.0211.v2

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

HIV-1: Tackling the Obstacles that Limit the Effectiveness of CRISPR-Cas9 Gene Editing of the T Cell Co-receptor CCR5DOI 10.20944/preprints201907.0211.v2Read

The therapeutic application of CRISPR/Cas9 technologies for HIVSemantic proximity Read

CRISPR/Cas9: a tool to eradicate HIV-1Semantic proximity Read

Application of CRISPR/Cas9-Based Gene Editing in HIV-1/AIDS TherapySemantic proximity Read

Genome editing of the HIV co-receptors CCR5 and CXCR4 by CRISPR-Cas9 protects CD4+ T cells from HIV-1 infectionSemantic proximity Read

CRISPR/Cas9: a double-edged sword when used to combat HIV infectionSemantic proximity Read

A CRISPR-Cas Cure for HIV/AIDSSemantic proximity Read

Inhibition of HIV-1 replication using the CRISPR/cas9-no NLS system as a prophylactic strategySemantic proximity Read

Current Challenges With Highly Active Antiretroviral Therapy and New Hope and Horizon With CRISPR ‐ CAS9 Technology for HIV TreatmentSemantic proximity Read

Delivering CRISPR to the HIV-1 reservoirsSemantic proximity Read

A combinational CRISPR/Cas9 gene-editing approach can halt HIV replication and prevent viral escapeSemantic proximity Read

Gene Editing of HIV-1 Co-receptors to Prevent and/or Cure Virus InfectionSemantic proximity Read

CRISPR Cas13a: A Potential Therapeutic Cure for HIV Infection in HumansSemantic proximity Read