Article

A dual role for the RNA helicase DHX34 in NMD and pre-mRNA splicing and its function in hematopoietic differentiation

2022-05-26

Abstract excerpt

<h4>ABSTRACT</h4> The DExD/H-box RNA helicase DHX34 is a Nonsense-mediated decay (NMD) factor that together with core NMD factors co-regulates NMD targets in nematodes and in vertebrates. Here, we show that DHX34 is also associated with the human spliceosomal catalytic C complex. Mapping of DHX34 endogenous binding sites using Cross-Linking Immunoprecipitation (CLIP) revealed that DHX34 is preferentially associat...

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Literature Corpus work: 72a3cc74-f9c8-526d-9466-dd20890efd4e
DOI: 10.1101/2022.05.26.492072

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