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Article

Clinical and mechanistic insights into the roles of DDX41 in haematological malignancies.

FEBS letters - 1 Nov 2022

Weinreb Joshua T, Bowman Teresa V

Abstract excerpt

DEAD-box Helicase 41 (DDX41) is a member of the DExD/H-box helicase family that has a variety of cellular functions. Of note, germline and somatic mutations in the DDX41 gene are prevalently found in myeloid malignancies. Here, we present a comprehensive and analytic review covering relevant clinical, translational and basic science findings on DDX41. We first describe the initial characterisation of DDX41...

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Share to DEAD-box RNA Helicases
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Share to Leukemia, Myeloid, Acute

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36036093
DOI: 10.1002/1873-3468.14487
PMCID: PMC9669125

Genes

DDX41

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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