Article

NucPosDB: a database of nucleosome positioning <i>in vivo</i> and nucleosomics of cell-free DNA

2021-11-25

Abstract excerpt

Nucleosome positioning is involved in many gene regulatory processes happening in the cell and it may change as cells differentiate or respond to the changing microenvironment in a healthy or diseased organism. One important implication of nucleosome positioning in clinical epigenetics is its use in the “nucleosomics” analysis of cell-free DNA (cfDNA) for the purpose of patient diagnostics in liquid biopsies. The...

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Literature Corpus work: 726340ca-bd83-58b1-82ec-b2d3a73b99cb
DOI: 10.1101/2021.11.24.469884

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