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TAM receptors control actomyosin dynamics in osteoclasts via RHOA-COFILIN-MYOSIN II signaling

2024-04-14

Abstract excerpt

The TAM family of receptor tyrosine kinases were recently identified to regulate bone homeostasis by controlling osteoblasts and bone formation. Despite extensive knowledge of TAM receptor function in the mononuclear phagocyte system, the role of TAM receptors in osteoclasts remains largely unknown. Here, we identify a physiological regulatory system including MERTK and TYRO3 in osteoclasts controlling RHOA-ROCK-C...

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Literature Corpus work
724f1b2d-32fc-53fe-bb4f-358abadba7b9
DOI
10.1101/2024.04.12.589232
Open publication

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TAM receptors control actomyosin dynamics in osteoclasts via RHOA-COFILIN-MYOSIN II signalingDOI 10.1101/2024.04.12.589232
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