Article

Atg8-LC3 controls systemic nutrient surplus signaling from flies to humans

2023-06-04

Abstract excerpt

Organisms experience constant nutritional flux, and homeostatic mechanisms evolved to operate at the nexus of extreme nutritional states - scarcity and surplus. Thus, we surmised that decoding bidirectional molecular switches that operate at the interface of scarcity response and surplus signaling will enable the development of strategies to treat disorders that arise from nutrient imbalance states. Adipocytes sec...

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Identifiers and source

Literature Corpus work: 723943c1-9445-5ac7-9343-1d617e3cfaee
DOI: 10.1101/2023.05.31.543119

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