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Development of an inhibiting antibody against equine interleukin 5 to treat insect bite hypersensitivity of horses

2022-11-10

Abstract excerpt

Insect bite hypersensitivity (IBH) is the most common allergic skin disease of horses. It is caused by insect bites of the Culicoides spp. which mediate a type I/IVb allergy with strong involvement of eosinophil cells. No specific treatment option is available so far. One concept could be the use of a therapeutic antibody targeting equine interleukin 5, the main activator and regulator of eosinophils. Therefore, a...

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Identifiers and source

Literature Corpus work
71c252ef-7a27-5da9-91f1-fdfaee17a5ce
DOI
10.21203/rs.3.rs-2234317/v1
Open publication

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