Article

Interleukin 5 dependent inflammatory eosinophil subtype involved in allergic insect bite hypersensitivity of horses

2023-05-11

Abstract excerpt

Eosinophils are known to play a crucial role in equine insect bite hypersensitivity (IBH), an allergic and pruritic dermatitis. Given the relevant role of eosinophils in disease pathology, a virus-like particle (VLP)-based vaccination targeting equine Interleukin (eIL)-5 has been shown to significantly reduce eosinophil levels in the blood and hence reduced IBH symptoms in horses. The aim of the present study was...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ef422350-bcdf-5fb6-953d-a3555492a1e3
DOI: 10.22541/au.168378134.48000256/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Interleukin 5 dependent inflammatory eosinophil subtype involved in allergic insect bite hypersensitivity of horsesDOI 10.22541/au.168378134.48000256/v1Read

Peripheral blood basophils are the main source for early interleukin-4 secretion upon in vitro stimulation with Culicoides allergen in allergic horses.Semantic proximity Read

Development of an inhibiting antibody against equine interleukin 5 to treat insect bite hypersensitivity of horsesSemantic proximity Read

Eosinophils from Physiology to Disease: A Comprehensive Review.Semantic proximity Read

Towards personalized medicine for the treatment of equine asthma.Semantic proximity Read

Multidimensional Analysis of Bronchoalveolar Lavage Cytokines and Mast Cell Proteases Reveals Interferon-γ as a Key Biomarker in Equine Asthma SyndromeSemantic proximity Read

Immunogenomic analysis of insect bite hypersensitivity in a model horse population.Semantic proximity Read

Lessons learned from targeting eosinophils in human disease.Semantic proximity Read

Expression of Interleukin-4 Receptor and CCL5 Chemokine is not Related to Insect Bite Hypersensitivity in HorsesSemantic proximity Read

Monitoring eosinophils to guide therapy with Biologics in Asthma: does the compartment matter?Semantic proximity Read

Investigating the epithelial barrier and immune signatures in the pathogenesis of equine insect bite hypersensitivitySemantic proximity Read

Genome-Wide Association Study of Insect Bite Hypersensitivity in Swedish-Born Icelandic Horses.Semantic proximity Read

Precision Medicine in Hymenoptera Venom Allergy: Diagnostics, Biomarkers, and Therapy of Different Endotypes and Phenotypes.Semantic proximity Read