Article
Immunogenomic analysis of insect bite hypersensitivity in a model horse population.
Veterinary immunology and immunopathology - 15 Apr 2013
Vychodilova Leona, Matiasovic Jan, Bobrova Olga, Futas Jan, Klumplerova Marie, Stejskalova Karla, Cvanova Michaela, Janova Eva, Osickova Jarmila, Vyskocil Mirko, Sedlinska Marketa, Dusek Ladislav, Marti Eliane, Horin Petr
Abstract excerpt
Equine insect bite hypersensitivity (IBH) is a seasonal IgE-mediated dermatosis caused by bites of insects of the genus Culicoides. A familial predisposition for the disease has been shown but, except for the MHC, the genes involved have not been identified so far. An immunogenomic analysis of IBH was performed in a model population of Old Kladruby horses, all living in the same environment. Clinical signs of IBH...
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