Article

Endogenous network modeling reveals mechanisms of repair Schwann cell decline and potential recovery targets

2026-05-13

Abstract excerpt

Schwann cells, the principal glial cells of the peripheral nervous system, play a central role in nerve repair following injury. Upon injury, mature Schwann cells dedifferentiate into repair Schwann cells. These processes are governed by complex gene regulatory networks, yet the quantitative dynamics of these processes remain unclear. Here, using a bottom-up systems biology approach, we constructed an endogenous r...

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Literature Corpus work: 71b46c33-ec54-540f-b2d7-cc77560e90d1
DOI: 10.64898/2026.05.09.723972

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