Article

Mitf is a Schwann Cell Sensor of Axonal Integrity that Drives Nerve Repair

2022-09-27

Abstract excerpt

<h4>Summary</h4> Schwann cells respond to acute axon damage by transiently transdifferentiating into specialized repair cells that restore sensorimotor function. However, the molecular systems controlling repair cell formation and function are not well defined and consequently it is unclear whether this form of cellular plasticity has a role in peripheral neuropathies. Here we identify Mitf as a transcriptional s...

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Literature Corpus work: 698d91ec-85df-52c1-bab1-843cd5b32b83
DOI: 10.1101/2022.09.25.509350

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