Article

Nerve injury converts Schwann cells in a persisting repair state in human neuroma tissue

2024-05-14

Abstract excerpt

Peripheral nerve injury (PNI) induces neuroma formation at the severed nerve stump resulting in impaired nerve regeneration and functional recovery in patients. So far, molecular mechanisms and cell types present in the neuroma impeding on regeneration have only sparsely been analyzed. Herein we compare resected human neuroma tissue with intact donor nerves from the same patient. Neuroma from several post-injury t...

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Literature Corpus work: c8596987-0dd8-5229-8379-e4c23d774352
DOI: 10.1101/2024.05.13.593891

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