Article

Exome Sequencing Revealed PDE11A as a Novel Candidate Gene for Early-Onset Alzheimer's disease

2020-11-13

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Alzheimer’s disease (AD) is a leading cause of dementia in the elderly and has become a major health issue. However, a large number of genetic risk factors remain undiscovered. <bold>Methods: </bold>To identify novel risk genes and better understand the molecular pathway underlying AD, whole-exome sequencing (WES) was performed in 215 early-onset AD (EOAD) patie...

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Literature Corpus work: 7185b71e-7b8c-5e94-bb75-09b975038a16
DOI: 10.21203/rs.3.rs-104541/v1

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