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Nonfamilial early-onset Alzheimer's disease associated with de novo PSEN1 mutation: A case report and review of the literature

2024-05-30

Abstract excerpt

<title>Abstract</title> <p>Background Alzheimer's disease (AD) is the most common cognitive disorder, and onset before the age of 65 is defined as early-onset AD (EOAD), accompanied with nonfamilial <italic>presenilin 1</italic> (<italic>PSEN1</italic>) mutation rarely reported. KCNQ2 is a transmembrane potassium channel gene is responsible for epilepsy, the relationship between KCNQ2 mutation and AD with epilep...

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Literature Corpus work: dc563d92-d652-5daf-87b1-ff44d47f2dad
DOI: 10.21203/rs.3.rs-4360435/v1

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