Article

Is the tryptophan codon of gene vif the Achilles’ heel of HIV-1?

2019-11-10

Abstract excerpt

To evaluate the impact of hypermutation to the HIV-1 dissemination at the population level we studied 7072 sequences HIV-1 gene vif retrieved from public databank. From this dataset 857 sequences were selected because they had associated values of CD4+ T lymphocytes counts and viral loads and they were used to assess the correlation between clinical parameters and hypermutation. We found that the frequency of stop...

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Literature Corpus work: 71644d2b-25c4-5787-bbcd-0d4998e64ff5
DOI: 10.1101/837419

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