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Article

Is the tryptophan codon of gene vif the Achilles' heel of HIV-1?

PloS one - 1 Jan 2020

Villanova Fabiola, Barreiros Marta, Leal Élcio

Abstract excerpt

To evaluate the impact of hypermutation on the HIV-1 dissemination at the population level we studied 7072 sequences HIV-1 gene vif retrieved from the public databank. From this dataset 854 sequences were selected because they had associated values of CD4+ T lymphocytes counts and viral loads and they were used to assess the correlation between clinical parameters and hypermutation. We found that the frequency of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32570272
DOI: 10.1371/journal.pone.0225563
PMCID: PMC7308096

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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