Article
Full-length title: Dramatic HIV DNA degradation associated with spontaneous HIV suppression and disease-free outcome in a young seropositive woman following her infection.
Scientific reports - 13 Feb 2020
Colson Philippe, Dhiver Catherine, Tamalet Catherine, Delerce Jeremy, Glazunova Olga O, Gaudin Maxime, Levasseur Anthony, Raoult Didier
Abstract excerpt
Strategies to cure HIV-infected patients by virus-targeting drugs have failed to date. We identified a HIV-1-seropositive woman who spontaneously suppressed HIV replication and had normal CD4-cell counts, no HIV-disease, no replication-competent virus and no cell HIV DNA detected with a routine assay. We suspected that dramatic HIV DNA degradation occurred post-infection. We performed multiple nested-PCRs...
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