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Article

The biased nucleotide composition of the HIV genome: a constant factor in a highly variable virus

6 Nov 2012

Abstract excerpt

Viruses often deviate from their hosts in the nucleotide composition of their genomes. The RNA genome of the lentivirus family of retroviruses, including human immunodeficiency virus (HIV), contains e.g. an above average percentage of adenine (A) nucleotides, while being extremely poor in cytosine (C). Such a deviant base composition has implications for the amino acids that are encoded by the open reading frames...

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PMID: 23131071
DOI: 10.1186/1742-4690-9-92

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