Article

SPITROBOT-2 advances time-resolved cryo-trapping crystallography to under 25 ms

2025-05-25

Abstract excerpt

We previously introduced the SPITROBOT, a protein crystal plunging system that enables reaction quenching via cryo-trapping with a time resolution in the millisecond range. Here we present the next generation, SPITROBOT-2, as an integrated benchtop device, condensed to approximately an A4 footprint. The user experience has been enhanced by the integration of a guiding beam and a sample-switch dial, to optimise sam...

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Literature Corpus work: 715e3cfa-271f-5c0f-942a-06522a51e187
DOI: 10.1101/2025.05.23.655289

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