Article

Identification of Low Population States in Cryo-EM Using Deep Learning

2021-11-07

Abstract excerpt

Cryo-EM has made extraordinary headway towards becoming a semi-automated, high-throughput structure determination technique. In the general workflow, high-to-medium population states are grouped into two- and three-dimensional classes, from which structures can be obtained with near-atomic resolution and subsequently analyzed to interpret function. However, low population states, which are also functionally import...

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Literature Corpus work: 60acb099-8334-50f9-ab09-b844f77ee0e2
DOI: 10.1101/2021.11.06.467553

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