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Targeting ferroptosis: a new therapeutic opportunity for kidney diseases

3 Jul 2024

Abstract excerpt

Ferroptosis is a form of non-apoptotic regulated cell death (RCD) that depends on iron and is characterized by the accumulation of lipid peroxides to lethal levels. Ferroptosis involves multiple pathways including redox balance, iron regulation, mitochondrial function, and amino acid, lipid, and glycometabolism. Furthermore, various disease-related signaling pathways also play a role in regulating the process of...

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PMID: 39021564
DOI: 10.3389/fimmu.2024.1435139

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