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JNK signalling regulates self-renewal of proliferative urine-derived renal progenitor cells via inhibition of ferroptosis

2022-08-24

Abstract excerpt

<h4>Summary</h4> With a global increase in chronic kidney disease patients, alternatives to dialysis and organ transplantation are needed. Stem cell-based therapies could be one possibility to treat chronic kidney disease. Here, we used multipotent urine-derived renal progenitor cells (UdRPCs) to study nephrogenesis. UdRPCs treated with the JNK inhibitor-AEG3482, displayed decreased proliferation and downregulate...

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Identifiers and source

Literature Corpus work
110a27b7-bbdd-53ec-89a6-2b143ac9ea28
DOI
10.1101/2022.08.24.505101
Open publication

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JNK signalling regulates self-renewal of proliferative urine-derived renal progenitor cells via inhibition of ferroptosisDOI 10.1101/2022.08.24.505101
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