Article

Modeling of Fabry disease nephropathy using patient derived human induced pluripotent stem cells and kidney organoid system

2022-11-18

Abstract excerpt

<title>Abstract</title> <p><bold>Objectives:</bold> To explore the possibility of kidney organoids generated using patient derived human induced pluripotent stem cells (hiPSC) for modeling of Fabry disease nephropathy (FDN). <bold>Methods:</bold> First, we generated hiPSC line using peripheral blood mononuclear cells (PBMCs) from two male FD-patients with different types of <italic>GLA</italic> mutation: a classi...

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Literature Corpus work: 82604cb3-2070-5119-ba32-0a0ecdbcf2a5
DOI: 10.21203/rs.3.rs-2259010/v1

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