Kidney Organoids as Disease Models: Strengths, Weaknesses and Perspectives

Abstract excerpt

Chronic kidney disease (CKD) is a major global health problem, as it affects 10% of the global population and kills millions of patients every year. It is therefore of the utmost importance to develop models that can help us to understand the pathogenesis of CKD and improve our therapeutic strategies. The discovery of human induced pluripotent stem cells (hiPSCs) and, more recently, the development of methods for...

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