Article

Temporal Changes in Morphology of the Auditory and Vestibular Organs in C57BL/6J (Cdh23ahl/ahl) Mice

2023-12-21

Abstract excerpt

C57BL/6J ( Cdh23 ahl/ahl ) mice present with progressive hearing loss (HL) and are homozygous for the Cdh23 gene variant (c.753A), which is responsible for HL in C57BL/6J ( Cdh23 ahl/ahl ) mice. In humans, the CDH23 gene is responsible for syndromic HL, such as congenital severe HL and bilateral vestibular dysfunction in Usher syndrome type 1D (USH1D), and non-syndromic HL, such as DFNB12, which is progressively i...

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Literature Corpus work: 70a8fd69-e00b-5e57-9108-227f8d18f604
DOI: 10.21203/rs.3.rs-3749543/v1

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