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Article

Differential effects of Cdh23(753A) on auditory and vestibular functional aging in C57BL/6J mice.

Neurobiology of aging - 1 Jul 2016

Mock Bruce E, Vijayakumar Sarath, Pierce Jessica, Jones Timothy A, Jones Sherri M

Abstract excerpt

The C57BL/6J (B6) mouse strain carries a cadherin 23 mutation (Cdh23(753A), also known as Ahl), which affects inner ear structures and results in age-related hearing loss. The B6.CAST strain harbors the wild type Cdh23 gene, and hence, the influence of Ahl is absent. The purpose of the present study was to characterize the effect of age and gender on gravity receptor function in B6 and B6.CAST strains and to...

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Source

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Identifiers

PMID: 27255811
DOI: 10.1016/j.neurobiolaging.2016.03.013
PMCID: PMC4893173

Genes

CAST

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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