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Article

Quantitative trait loci on chromosome 5 for susceptibility to frequency-specific effects on hearing in DBA/2J mice.

Experimental animals - 1 Jan 2015

Suzuki Sari, Ishikawa Masashi, Ueda Takuya, Ohshiba Yasuhiro, Miyasaka Yuki, Okumura Kazuhiro, Yokohama Michinari, Taya Choji, Matsuoka Kunie, Kikkawa Yoshiaki

Abstract excerpt

The DBA/2J strain is a model for early-onset, progressive hearing loss in humans, as confirmed in the present study. DBA/2J mice showed progression of hearing loss to low-frequency sounds from ultrasonic-frequency sounds and profound hearing loss at all frequencies before 7 months of age. It is known that the early-onset hearing loss of DBA/2J mice is caused by affects in the ahl (Cdh23(ahl)) and ahl8...

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Source

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Identifiers

PMID: 25765874
DOI: 10.1538/expanim.14-0110
PMCID: PMC4547997

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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