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<i>Muc6</i> -expressing gastric isthmus progenitors contribute to regeneration and metaplasia supported by myeloid-mesenchymal interactions

2025-04-16

Abstract excerpt

<h4>Summary</h4> Gastric mucosal homeostasis is maintained by tissue-resident stem and progenitor cells residing in the isthmus region. Following mucosal injury, surviving cells contribute to regeneration, coinciding with characteristic pathological changes such as atrophic gastritis and metaplasia. To comprehensively understand the cellular dynamics involved in this process, we performed single-cell and spatial...

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Identifiers and source

Literature Corpus work
70a6500a-a3fe-5354-ba6a-d8b8f32cb575
DOI
10.1101/2025.04.15.648856
Open publication

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<i>Muc6</i> -expressing gastric isthmus progenitors contribute to regeneration and metaplasia supported by myeloid-mesenchymal interactionsDOI 10.1101/2025.04.15.648856
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