Article
A spatially mapped gene expression signature for intestinal stem-like cells identifies high-risk precursors of gastric cancer
2023-09-22
Abstract excerpt
<h4>ABSTRACT</h4> <h4>Objective</h4> Gastric intestinal metaplasia ( GIM ) is a precancerous lesion that increases gastric cancer ( GC ) risk. The Operative Link on GIM ( OLGIM ) is a combined clinical-histopathologic system to risk-stratify patients with GIM. The identification of molecular biomarkers that are indicators for advanced OLGIM lesions may improve cancer prevention efforts. <h4>Methods</h4> Thi...
Topics
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- Cancer-Associated Fibroblasts
- Cancer Cells and Metastasis
- Cancer Genomics and Diagnostics
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Gastric Cancer Management and Outcomes
- Genetic factors in colorectal cancer
- Helicobacter pylori-related gastroenterology studies
- Single-cell and spatial transcriptomics
Identifiers and source
- Literature Corpus work
- f3ed0994-5468-53d9-8ee6-eaaaa62ab19c
- DOI
- 10.1101/2023.09.20.558462
