Article

Distant lymph nodes compensate for resected tumor-draining lymph nodes during cancer immunotherapy

2023-09-22

Abstract excerpt

<h4>Summary</h4> Lymphatic transport facilitates the presentation of cancer antigens in tumor-draining lymph nodes (tdLNs), leading to T cell activation and the generation of systemic anti-cancer immune surveillance. Surgical removal of tdLNs to control cancer progression is routine in clinical practice. However, whether removing tdLNs impairs immune checkpoint blockade (ICB) is still controversial. Our analysis...

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Literature Corpus work: 709a0cfa-268b-58a3-bbe6-739675a20725
DOI: 10.1101/2023.09.19.558262

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