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Article

Association Between <i>Clostridioides difficile</i> Test Positivity and Incident Colorectal Cancer in a Multisite Hospital-Based Retrospective Cohort Analysis

2026-02-24

Abstract excerpt

<h4>Introduction</h4> Sporadic colorectal cancer (CRC) remains a significant driver of worldwide morbidity and mortality. Environmental factors associated with CRC are increasingly well-described and now include generalized colonic dysbiosis and individual enteric bacteria. Clostridioides difficile is one such species, with recent mouse model work suggesting prolonged exposure to C. difficile toxin B is conduci...

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Literature Corpus work
70833257-f6e9-564f-be37-044a3af640b7
DOI
10.64898/2026.02.19.26346648
Open publication

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