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Article

Enterotoxigenic Bacteroides fragilis Induces Host Genotype-Specific Colonic Epithelial and Immune Responses in Mice.

The Journal of infectious diseases - 3 Aug 2026

Southward Taylor, Zhuang Yongbao, Tam Ada, Minsky Hana, Ferri Jacqueline, Michel John, Wu Shaoguang, Wu Xinqun, Larman Tatianna, Housseau Franck, White James R, Sears Cynthia L, Queen Jessica

Abstract excerpt

BACKGROUND: Colorectal cancer pathogenesis involves complex interactions between multiple risk factors including somatic mutations and microbial dysbiosis. A number of individual microbiota members have been implicated in colorectal cancer, including enterotoxigenic strains of Bacteroides fragilis (ETBF). Enterotoxigenic Bacteroides fragilis promotes inflammation in mouse models, which has been mechanistically...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 42089362
DOI: 10.1093/infdis/jiag247
PMCID: PMC13431769

Genes

BRAF

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