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Antibiotics promote susceptibility to <i>C. difficile</i> infection through a CCR5-dependent immune response

2026-06-29

Abstract excerpt

<h4>ABSTRACT</h4> Antibiotics (ABXs) represent the current standard of care for treating Clostridioides difficile infection (CDI). Paradoxically, ABX-induced dysbiosis is the primary risk factor for CDI, as disruption of the colonic microbial ecosystem creates an opportunity for C. difficile colonization. Given that ABXs can also alter immune responses, we investigated whether ABXs prime the colonic immune mili...

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Literature Corpus work
c8d678d1-3631-5555-935f-b90689897743
DOI
10.64898/2026.06.24.734321
Open publication

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Antibiotics promote susceptibility to <i>C. difficile</i> infection through a CCR5-dependent immune responseDOI 10.64898/2026.06.24.734321
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