Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Vascular endothelial growth factor-A specifies formation of native collaterals and regulates collateral growth in ischemia.

Circulation research - 24 Oct 2008

Clayton Jason A, Chalothorn Dan, Faber James E

Abstract excerpt

The density of native (preexisting) collaterals and their capacity to enlarge into large conduit arteries in ischemia (arteriogenesis) are major determinants of the severity of tissue injury in occlusive disease. Mechanisms directing arteriogenesis remain unclear. Moreover, nothing is known about how native collaterals form in healthy tissue. Evidence suggests vascular endothelial growth factor (VEGF), which is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cerebrovascular Circulation
Share to Femoral Artery

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Infarction, Middle Cerebral Artery

Share to Ischemia

Share to Ligation

Share to Regional Blood Flow

Share to Vascular Endothelial Growth Factor Receptor-1

Share to Vascular Endothelial Growth Factor Receptor-2

Source

Open in PubMed Open full text

Identifiers

PMID: 18802023
DOI: 10.1161/CIRCRESAHA.108.181115
PMCID: PMC2729271

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Vascular endothelial growth factor-A specifies formation of native collaterals and regulates collateral growth in ischemia.PMID 18802023Read ↗

Development of Pial Collaterals by Extension of Pre-existing Artery TipsSemantic proximity Read ↗

Vasculogenesis and Angiogenesis in VEGF Receptor-1 Deficient Mice.Semantic proximity Read ↗

Vascular development: cellular and molecular regulationSemantic proximity Read ↗

Signaling Role of Pericytes in Vascular Health and Tissue HomeostasisSemantic proximity Read ↗

Therapeutic Potential of Endothelial Colony Forming Cells in Ischemic Disease: Strategies to Improve Their Regenerative EfficacySemantic proximity Read ↗

The onset of PI3K-related vascular malformations occurs during angiogenesis and is prevented by the AKT inhibitor miransertib.Semantic proximity Read ↗

Ischemia is not required for arteriogenesis in zebrafish embryos.Semantic proximity Read ↗

p27(kip1) Knockout enhances collateralization in response to hindlimb ischemia.Semantic proximity Read ↗

Transcriptomics of Post-Stroke Angiogenesis in the Aged BrainSemantic proximity Read ↗

Therapeutic Potential of Endothelial Colony-Forming Cells in Ischemic Disease: Strategies to Improve their Regenerative Efficacy.Semantic proximity Read ↗

Flt-1 (VEGFR-1) coordinates discrete stages of blood vessel formation.Semantic proximity Read ↗

Molecular Controls of Arterial MorphogenesisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.