Article

Single-cell interactomes of the human brain reveal cell-type specific convergence of brain disorders

2019-03-24

Abstract excerpt

The reference human interactome has been instrumental in the systems-level study of the molecular inner workings of the cell, providing a framework to analyze the network context of disease associated gene perturbations. However, reference organismal interactomes do not capture the tissue- and cell type-specific context in which proteins and modules preferentially act. Emerging single-cell profiling technologies,...

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Literature Corpus work: 70016077-9eab-5ad5-a683-731965878b53
DOI: 10.1101/586859

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