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Article

Genetic diversity in the collaborative cross model recapitulates human West Nile virus disease outcomes.

mBio - 5 May 2015

Graham Jessica B, Thomas Sunil, Swarts Jessica, McMillan Aimee A, Ferris Martin T, Suthar Mehul S, Treuting Piper M, Ireton Renee, Gale Michael, Lund Jennifer M

Abstract excerpt

UNLABELLED: West Nile virus (WNV) is an emerging neuroinvasive flavivirus that now causes significant morbidity and mortality worldwide. The innate and adaptive immune responses to WNV infection have been well studied in C57BL/6J inbred mice, but this model lacks the variations in susceptibility,...

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Source

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Identifiers

PMID: 25944860
DOI: 10.1128/mBio.00493-15
PMCID: PMC4436067

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25944860-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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