Article

Immunoediting on the Brink: Dynamic Relationship Between Tumor Genotype and Microenvironment as Determinant of Immunotherapy Effectiveness in an informative case report of Lynch Syndrome

2024-04-05

Abstract excerpt

<h4>Background: </h4> Lynch syndrome is an autosomal-dominant inherited condition that significantly increases the risk of developing cancer; within the Lynch syndrome spectrum, Muir-Torre syndrome is an autosomal-dominant genodermatosis, associated with keratoacanthomas and sebaceous neoplasms (adenoma, carcinoma or epithelioma). Both are characterized by the presence of defects in mismatch repair genes resulting...

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Literature Corpus work: 6fefd3b4-eec1-520b-9789-a61e38390431
DOI: 10.21203/rs.3.rs-4194990/v1

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