Article
Genetic instability in the tumor microenvironment: a new look at an old neighbor
30 Jul 2015
Abstract excerpt
The recent exponential increase in our knowledge of cellular and molecular mechanisms involved in carcinogenesis has largely failed to translate into new therapies and clinical practices. This lack of success may result in part from the fact that most studies focus on tumor cells as potential therapeutic targets and neglect the complex microenvironment that undergoes profound changes during tumor development....
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