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<i>Leishmania</i> parasite arginine deprivation response pathway influences the host macrophage lysosomal arginine sensing machinery

2021-09-01

Abstract excerpt

Extensive interaction between the host and pathogen metabolic networks decidedly shapes the outcome of infection. Infection with Leishmania donovani , an intracellular protozoan parasite, leads to a competition for arginine between the host and the parasite. L. donovani transports arginine via a high-affinity transporter Ld AAP3, encoded by the two genes LdAAP3.1 and Ld AAP3.2. Earlier reports show that upon...

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Literature Corpus work
6fcbeaaf-8266-586b-8433-e20d05e4a8ba
DOI
10.1101/2021.09.01.458453
Open publication

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<i>Leishmania</i> parasite arginine deprivation response pathway influences the host macrophage lysosomal arginine sensing machineryDOI 10.1101/2021.09.01.458453
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