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<i>Leishmania</i> and the Macrophage: A Multifaceted Interaction

1 Jan 2015

Abstract excerpt

Leishmania, the causative agent of leishmaniases, is an intracellular parasite of macrophages, transmitted to humans via the bite of its sand fly vector. This protozoan organism has evolved strategies for efficient uptake into macrophages and is able to regulate phagosome maturation in order to make the phagosome more hospitable for parasite growth and to avoid destruction. As a result, macrophage defenses such...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 25598341
DOI: 10.2217/fmb.14.103

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