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Article

Arginine homeostasis and transport in the human pathogen Leishmania donovani.

The Journal of biological chemistry - 24 Jul 2009

Darlyuk Ilona, Goldman Adele, Roberts Sigrid C, Ullman Buddy, Rentsch Doris, Zilberstein Dan

Abstract excerpt

Arginine is an essential amino acid for the human pathogen Leishmania but not to its host. Thus, the mechanism by which this protozoan parasite regulates cellular homeostasis of arginine is critical for its survival and virulence. In a previous study, we cloned and functionally characterized a high affinity arginine-specific transporter, LdAAP3, from Leishmania donovani. In this investigation, we have...

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Identifiers

PMID: 19439418
DOI: 10.1074/jbc.M901066200
PMCID: PMC2740405

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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