Article
A novel high‐affinity arginine transporter from the human parasitic protozoan <i>Leishmania donovani</i>
21 Feb 2006
Abstract excerpt
We describe the first functional and molecular characterization of an amino acid permease (LdAAP3) from the human parasitic protozoan Leishmania donovani, the causative agent of visceral leishmaniasis in humans. This permease contains 480 amino acids with 11 predicted trans-membrane domains. Expressing LdAAP3 in Saccharomyces cerevisiae mutants revealed that LdAAP3 codes for a high-affinity arginine transporter...
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