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TransLeish: Identification of membrane transporters essential for survival of intracellular <i>Leishmania</i> parasites in a systematic gene deletion screen

2024-06-25

Abstract excerpt

<h4>Summary</h4> For the protozoan parasite Leishmania , completion of its life cycle requires sequential adaptation of cellular physiology and nutrient scavenging mechanisms to the different environments of a sand fly alimentary tract and the acidic mammalian host cell phagolysosome. Transmembrane transporters are the gatekeepers of intracellular environments, controlling the flux of solutes and ions across mem...

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Literature Corpus work
d0f0484e-1a43-5d18-863b-b120a9fd6fe9
DOI
10.1101/2024.06.21.600025
Open publication

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TransLeish: Identification of membrane transporters essential for survival of intracellular <i>Leishmania</i> parasites in a systematic gene deletion screenDOI 10.1101/2024.06.21.600025
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